carbohydrate oxidase

pdb 3rj8

PhoD

pdb 2yeq

McpS ligand binding domain

pdb 2yfa

FMN-binding protein

pdb 3awh

FKBP22

pdb 3b09

BACE

pdb 3udh

XEG

pdb 3vl8

biotin protein ligase

pdb 4dq2

mouse thymidylate synthase

pdb 4e5o

Laccase

pdb 3t6v

BF4112

pdb code 3cew

"Described herein is the sum of all human knowledge of BF4112; this protein takes the romantic mystery of biochemistry to a whole new level. BF4112 is a dimeric metalloprotein from Bacteroides fragilis, the most common bacterial pathogen in anaerobic human infections. It is a representative of a family of proteins from across bacteria, archea, and eukarya. The biological function of BF4112 is currently unknown, but it was structurally characterized due to its unique primary sequence. Recent investigations have identified a Tyr-Cys crosslink, a redox active protein cofactor, in the putative active site of BF4112 (1). Based on this evidence, it has been suggested that BF4112 may be a peroxidase or oxygenase involved in protection from reactive oxygen species, essential for B. fragilis pathogenicity in nanomolar oxygen concentration environments. "

(1) Martinie, R. J.; Godkumbura, P. I.; Porter, E. G.; Divakaran, A.; Burkhart, B. J.; Wertz, J. T.; Benson, D. E. Metallomics. In preparation.

Human Serine Threonine Kinase-10 (LOK)

PDB code 4AOT

Fungal lipase from Thermomyces(Humicola) lanuginosa

PDB code 4EA6

ABC-type phosphate transport system, periplasmic component (LVIS_0633)

PDB code 4ECF

human carbonic anhydrase isozyme II

PDB code 3SBH

Y248A mutant of C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus

PDB code 3VJD

shwanavidin low affinity mutant (F43A)

PDB code 3T2X

human alpha-defensin 1, HNP1 (G17A mutant)

PDB 4DU0

Human Aurora B Kinase in complex with INCENP and VX-680

PDB code 4AF3

What's in a name?

(image courtesy of http://www.fanboy.com/2007/07/the-curse-of-the-red-shirt.html)

This blog houses brief descriptions of proteins to be used to fill out the bracket of 64 for the Protein of the Year 2012 competition. Though many are interesting, important, and essential, they will serve a sacrifice for the greater good of my students' proteins in the competition.

"Ah..." you say, "...but what do you mean by red shirts?" For your answer, watch a little Star Trek, or take a look at what omniscient Wikipedia has to say.